LONG-TERM POLARIZATION OF ALVEOLAR MACROPHAGES TO A PROFIBROTIC PHENOTYPE AFTER INHALATION EXPOSURE TO MULTI-WALL CARBON NANOTUBES.

Long-term polarization of alveolar macrophages to a profibrotic phenotype after inhalation exposure to multi-wall carbon nanotubes.

BACKGROUND:Nanomaterials are widely used in various fields.Although the toxicity of carbon nanotubes (CNTs) in pulmonary tissues has been demonstrated, the toxicological effect of CNTs on the immune system in the lung remains unclear.METHODS AND FINDING:In this study, exposure to Taquann-treated multi-walled CNTs (T-CNTs) was performed Hair Accesso

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Outcomes in Dogs with Multiple Sites of Cervical Intervertebral Disc Disease Treated with Single Ventral Slot Decompression

In dogs with acute myelopathy but showing multiple sites of spinal compression from intervertebral disc disease (IVDD) on Pressure Prevention Mattress Covers imaging, one approach is surgical decompression of the single acute disc extrusion while ignoring other previously extruded or protruded discs.However, little is known regarding the outcomes o

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Design margins in industrial practice

As products are being developed over time and across organisations, the risk for unintended accumulation and mis-conception of margins allocated may occur.Accumulation of margins can result in over design, but also add risk due to under allocation.This paper describes the different terminology used in one organisation and shows the different roles

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